Abstract
A series of 1-(heteroarylthioalkyl)-4-benzylpiperidines was rapidly synthesized through the use of parallel synthesis to investigate the binding affinity for the NR1A/2B receptor subtype.
MeSH terms
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Animals
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Excitatory Amino Acid Antagonists / chemical synthesis*
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Excitatory Amino Acid Antagonists / pharmacology
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Oxidopamine
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Piperidines / chemical synthesis*
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Piperidines / pharmacology
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Rats
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Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors*
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Structure-Activity Relationship
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Sympathectomy, Chemical
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Sympatholytics
Substances
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Excitatory Amino Acid Antagonists
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Piperidines
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Receptors, N-Methyl-D-Aspartate
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Sympatholytics
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Oxidopamine